Phenylpropanoids and polyketides
Medchemexpress LLC 6-Hydroxyflavone | 6665-83-4 | 1 ML
6-Hydroxyflavone is an orally effective flavonoid compound. It demonstrates anti-inflammatory effects by inhibiting LPS-induced NO production and promotes osteoblast differentiation by activating AKT, ERK 1/2, and JNK signaling pathways. Additionally, it offers kidney protective effects, inhibits bovine hemoglobin (BHb) glycosylation, and enhances GABA-induced current through specific GABAA receptor subtypes, contributing to an anti-anxiety role. For research use only.
- Orally effective flavonoid compound.
- Exhibits anti-inflammatory properties.
- Promotes osteoblast differentiation.
- Inhibits bovine hemoglobin (BHb) glycosylation.
- Offers kidney protective effects.
- Enhances GABA-induced current via specific GABAA receptors (anti-anxiety).
- Maintains cell viability at concentrations up to 50 μM.
- Tested in various cell-based and animal models.
Medchemexpress LLC 6-Hydroxyflavone | 6665-83-4 | 500 MG
6-Hydroxyflavone is an orally effective flavonoid compound. It inhibits LPS-induced NO production and has anti-inflammatory effects. It promotes osteoblast differentiation by activating AKT, ERK 1/2, and JNK signaling pathways. 6-Hydroxyflavone also shows an inhibitory effect on bovine hemoglobin (BHb) glycosylation and has a kidney protective effect. Additionally, it enhances GABA-induced current through the Benzodiazepine sites of γ-aminobutyric acid (GABAA) receptors, with a clear preference for α2- and α3- subtypes, playing an anti-anxiety role.
- Orally effective flavonoid compound
- Anti-inflammatory effects
- Promotes osteoblast differentiation
- Inhibits bovine hemoglobin (BHb) glycosylation
- Kidney protective effect
- Enhances GABA-induced current through GABAA receptors, showing anti-anxiety effects
- Purity: 99.92%
- Appearance: Solid
- Color: Light yellow to yellow
Selleck Chemical LLC 7-Hydroxyflavone S5380-25mg
7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0 015 M and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2 It also has excellent antioxidant properties and great potential to be applied as medicines
Medchemexpress LLC Troxerutin | 7085-55-4 | 98.0% | 742.68 | 10 G
Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins. It is capable of inhibiting the production of reactive oxygen species (ROS) and depressing ER stress-mediated NOD activation.
- Inhibits ROS production
- Depresses ER stress-mediated NOD activation
- Lowers body weight and improves metabolic parameters
- Restores glucose intolerance and insulin signaling
- Attenuates vascular damages
Selleck Chemical LLC 3-Hydroxyflavone S4790-25mg
3-Hydroxyflavone (Flavon-3-ol 3-HF 3-Hydroxy-2-phenylchromone) is the simplest molecule of the flavonol class that is usually used in synthesis of biologically active molecules
Medchemexpress LLC 4'-Hydroxyflavone | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 g/mol | C15H10O3 | 10 MG
4'-Hydroxyflavone is a flavone-class small molecule used in research as an aldose reductase inhibitor. It is supplied as a high-purity research reagent for biochemical assays and is commonly used in enzyme inhibition studies, structure-activity relationship (SAR) investigations, and small-molecule screening.
- High purity (97.0%)
- Molecular formula C15H10O3
- Molecular weight 238.24 g/mol
- CAS number 4143-63-9
- Reported aldose reductase IC50 12 μM
- Suitable for enzyme inhibition assays and SAR studies
Medchemexpress LLC 5-Hydroxyflavone | 491-78-1 | 99.8% | 238.24 | 25 MG
5-Hydroxyflavone is a flavonoid ligand that shows no cytotoxic activity against MCF-7, FaDU, MDA-MB-435S, U87, RPE-1, and HEK293 cells.
- Flavonoid ligand
- No cytotoxic activity against MCF-7, FaDU, MDA-MB-435S, U87, RPE-1, and HEK293 cells
- Solid, light yellow to yellow appearance
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 2 years, -20°C for 1 year
Medchemexpress LLC 5-Hydroxyflavone | 491-78-1 | 99.8% | 238.24 | 50 MG
5-Hydroxyflavone is a flavonoid ligand that has demonstrated no cytotoxic activity against several cell lines, including MCF-7, FaDU, MDA-MB-435S, U87, RPE-1, and HEK293 cells.
- Flavonoid ligand
- No cytotoxic activity against various cell lines
- Solid appearance, light yellow to yellow color
- Soluble in DMSO
- Long-term storage recommended at -20°C for powder and -80°C in solvent
Selleck Chemical LLC 7-Hydroxyflavone S5380-1g
7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0 015 M and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2 It also has excellent antioxidant properties and great potential to be applied as medicines
TARGETMOL CHEMICALS INC 4-Hydroxyflavone 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 4'-Hydroxyflavone is a flavonoid compound isolated from the roots of Scutellaria baicalensis with anti-inflammatory activity. Purity 99.42%
Medchemexpress LLC Chrysin-7-O-glucuronide | 35775-49-6 | 1 ML
Chrysin-7-O-glucuronide is a flavonoid extracted from *Scutellaria baicalensis*, possessing antioxidant activity. It inhibits α-glucosidase and α-amylase, suppresses NF-κB signaling activity, scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. This compound is suitable for research related to type 2 diabetes and severe acute pancreatitis-induced intestinal barrier injury.
- Inhibits alpha-glucosidase and alpha-amylase
- Suppresses NF-κB signaling activity
- Scavenges free radicals
- Acts as a tight junction protector
- Mitigates intestinal mucosal barrier injury
- Restores ZO-1 expression and tight junction structure
- Ameliorates SAP-induced intestinal mucosal barrier injury in rats
Medchemexpress LLC Chrysin (5,7-Dihydroxyflavone) | 480-40-0 | 99.8% | C15H10O4 | 1 ML
Chrysin is a naturally occurring flavonoid found in passion flowers, honey, and propolis. It is an estrogen blocker intended for research use only and acts as a potential therapeutic and preventive agent against the proliferation and invasion of various human cancer cells. It has shown anti-carcinogenic effects by inhibiting ovarian cancer cell proliferation, inducing cell death through increased reactive oxygen species (ROS) production, elevated cytoplasmic Ca2+ levels, and loss of mitochondrial membrane potential (MMP).
- Activates MAPK and PI3K/AKT pathways
- Suppresses tumor growth by regulating canonical Wnt and nuclear factor NF-κB signaling cascades
- Stimulates phosphorylation of AKT and P70S6K proteins
- Activates phospho-ERK1/2, p38, and JNK proteins within the MAPK pathway in ovarian cancer cells
Medchemexpress LLC Chrysin (Standard) | 480-40-0 | 100.0% | C₁₅H₁₀O₄ | 50 MG
Chrysin (Standard) is the analytical standard of Chrysin, intended for research and analytical applications. It is known as one of the most well-known estrogen blockers.
- Analytical standard grade
- Supplied for assay reference
- Commonly utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
Selleck Chemical LLC Chrysin S2281-100mg
Chrysin (NSC 407436) is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea)